Seminar Series

The STROBE Seminar Series provides students and participants with a variety of research and professional development experiences that will enhance understandings of the imaging science modalities across all STROBE disciplines by inviting experts in the imaging sciences fields to showcase their research. Participants will also expand leadership and management skillsets with professional development workshops, and increase communication skills by showcasing research in short presentation format. This seminar series enhances integration between the different scientific thrusts of STROBE (electron, x-ray, and nano imaging modalities and STROBE’s underpinning technologies) and strengthens the ties between STROBE institutions. Attendance and a final project report are required to receive full credit.

Spring 2018 Instructors: Dr. Markus Raschke and Dr. Tess Eidem

Location: CU JILA Foothills Room, or streamed via GoToMeeting to all STROBE Nodes.

Time: 3pm PT | 4pm MT | 6pm ET

Course Listings:

  • CU Boulder-PHYS 7810-005 or ECEN 5006-002
  • UCLA - Physics 269D
  • UC Berkeley - Chem 298, section 19, #42407
  • UC Irvine - Physics 261B
Title Date Event Details
STROBE Seminar: Introduction to Seminar, IDP, and StrengthsFinder Jan 22, 2018 Dr. Tess Eidem, STROBE Assistant Director of Education, University of Colorado Boulder

The first STROBE Seminar of 2018 will focus on developing your IDP, or Individual Development Plan. Prior to the first seminar, seminar attendees will receive a link to a StrengthsFinder self-assessment to hone in on your skills and how they will help you succeed in your future career. An in-person facilitator at Boulder, Berkeley and UCLA will explain the StrengthsFinder and IDP results for students and postdocs.

STROBE and SPC Seminar: UCI-Invited Science Communication / NPR Speaker Jan 29, 2018 Sandra Tsing Loh, NPR

Among her many roles as an actress, author, and artist, Sandra Tsing Loh is the host of the daily NPR radio program, The Loh Down on Science, where she delivers the latest in science in a humorous, yet informative minute-long broadcast. In addition, she leads the Science Communication course at UC Irvine, where she teaches young scientists how to communicate their work to the general public and avoid pitfalls in conveying complicated and controversial science. During this seminar, Sandra will show how scientists can share their projects in fun and engaging ways without relying on difficult, technical terminology.

Hosted by: Franklin Dollar at UC Irvine

STROBE Seminar: Project Management Feb 05, 2018 Dr. Dan Moorer, Director of Engineering Management Program, University of Colorado Boulder

Leadership and project management skills are essential for a successful career in STEM across academia, industry, and government, yet many STEM trainees often overlook opportunities to build fundamental professional skills that will propel their success in their future careers.

Dr. Moorer, Director of the Lockheed Martin Engineering Management Program at CU Boulder, will outline the importance of leadership and project management, highlight their use in STEM careers, and share information on formal training to improve these skills.

Hosted by CU Boulder and broadcast across STROBE nodes.
Everyone welcome to attend!

STROBE Seminar: Entangled Photon Imaging for Biological Materials Feb 12, 2018 Dr. Ralph Jimenez, NIST, JILA, and University of Colorado Boulder

Fluorescence imaging is a widely used method for resolving molecular events in cells and tissues.  The development of genetically-encoded fluorophores and a detailed understanding of their photophysics is critical for quantitative bioimaging. Dr. Jiminez will provide an overview of the properties of fluorescent proteins and biosensors and describe some of his research to quantify and improve the performance of these important biological probes. Dr. Jimenez will also describe a new research direction aiming to dramatically enhance bioimaging by employing quantum optics techniques.

Hosted by CU Boulder and broadcast across STROBE nodes.
Everyone is welcome to attend!

STROBE Seminar: Overcoming Diffraction Limitations in Optical Imaging Feb 19, 2018 Dr. Rafael Piestun, STROBE Faculty, University of Colorado Boulder

Optical computational imaging seeks enhanced performance and new functionality by the joint design of illumination, optics, detectors, and reconstruction algorithms. In this talk we discuss how this approach helps overcome the diffraction limit in fluorescence microscopy. Abbe’s resolution limit has been overcome after more than 130 years enabling unprecedented opportunities for optical imaging at the nanoscale. Fluorescence imaging using photoactivatable or photoswitchable molecules within computational optical systems offers single molecule sensitivity within a wide field of view from far field measurements. The advent of three-dimensional point spread function engineering associated with optimal reconstruction algorithms provides a unique approach to further increase resolution in three dimensions. Compressive imaging techniques further enable resolution of dense emitters and enable acceleration of the super-resolution data collection.

Hosted by CU Boulder and broadcast across STROBE nodes.
Everyone is welcome to attend!

STROBE and SPC Seminar - Hands on Python Workshop: Image Analysis in the Jupyter Notebook Feb 26, 2018 Antonino Ingargiola, UCLA

Link to Workshop Materials:

This hands-on workshop will give students a taste of modern scientific computing in python using the Jupyter Notebook environment. Jupyter notebooks are executable documents that interleave narrative (rich text, math equations, figures, links) with code. The notebook workflow ties together high-level descriptions of the analysis, code and results in a single document that is easy to share or re-run. Even beginners can read and re-run analyses modifying parameters and exploring the effect on the results, either on the cloud or on personal computers. In this workshop we will interactively explore a single-molecule fluorescence microscopy video, performing tasks such as background subtraction, denoising, region of interest extraction, segmentation and analysis of blinking time-trajectories (on-off trajectories) of individual emitters. We will use numpy, scipy, matplotlib, pandas and more. Some basic experience with python is preferred. The analysis will be performed on a cloud service accessed with own laptop (browser-only, no installation required).

All participants are required to register and test the login prior to the workshop. Users without a working log-in will not be able to participate.

For registration go to

Registration deadline February 19, 2018

Publishing chemistry and materials research in Nature: an editor’s perspective Mar 02, 2018 Claire Hansell , Nature

Talk title: Publishing chemistry and materials research in Nature: an editor’s perspective


The time between manuscript submission and the binary outcomes of acceptance or rejection can often seem like a black box of intrigue, witchcraft, denial, confusion and much more. However, that is not the intended external face of peer review, and editors make judgements on what is best for any given manuscript every day based on just a few rational principles. Claire Hansell is a senior editor at Nature, previously at Nature Chemistry, and her talk will (hopefully) enlighten as to what goes on at an editor’s desk, with a specific focus on what editors at Nature are looking for in submissions.

STROBE Seminar: Modern Electron Microscopy: Atomic Imaging Mar 05, 2018 Dr. John Spear, UCLA

There have been numerous recent advancements on the TItan platform TEM for high resolution imaging in both Materials Science applications and also cryo-EM for protein structure determination. Not only have there been improvements in the technology itself but also int eh degree of automation in these instruments lowering the expertise needed for acquiring high quality datasets. 

Hosted by UCLA and broadcast across STROBE nodes.

Everyone is welcome to attend!

STROBE and SPC Seminar: Strategies for Effective Mentoring Mar 12, 2018 Linda von Hoene, Sabrina Soracco, University of California Berkeley

The purpose of this workshop is to assist graduate students and other STROBE participants in working effectively within the context of mentoring relatinoships with faculty, graduate students, and udnergraduates. Participants will learn about the importance of mentoring both to mentors and mentees, how to initiate mentoring relationships and keep them on track, and how to address problems that may arise. 

Hosted by UC Berkeley and broadcast across STROBE nodes. Everyone is welcome to attend!

STROBE Seminar: Characterizing Disordered Solids with Electron Microscopy Mar 19, 2018 Dr. Mary Scott, STROBE Faculty, University of California Berkeley

Owing to their lack of long-range order, measuring local structural variation in amorphous materials is challenging. Electron microscopy is uniquely able to characterize ordering and symmetry in disordered materials at the 2-5 nm length scale, enabling new insight into this class of materials.

Hosted by UC Berkeley and broadcast across STROBE nodes. Everyone is welcome to attend!



STROBE Seminar: Solving protein structure with laser-controlled electron beams (phase contrast electron microscopy) Apr 02, 2018 Dr. Osip Schwartz, University of California Berkeley, Postdoc in Dr. Holger Müller’s group

Transmission electron microscopy of frozen-hydrated specimens (cryo-EM) enabled atomic-resolution reconstruction of biological macromolecules. However, thin soft matter specimens are almost transparent to the electron beam and are extremely sensitive to radiation damage. This hinders the reconstruction of protein complexes that are either too small or too structurally heterogeneous to be readily discerned in electron micrographs. The visibility of biological macromolecules in cryo-EM images can be improved via electron interferometry, similarly to Zernike phase contrast in optical microscopy. We develop laser-based electron interferometry tools to enable Zernike phase contrast in electron microscopy. Laser coherent control of electron beams holds the promise of expanding the class of protein complexes amenable to cryo-EM reconstruction. Initial demonstration experiments are currently underway.

Hosted by UC Berkeley and broadcast across STROBE nodes.

Everyone is welcome to attend!

STROBE Seminar: Graduate Student 3-Minute Thesis Talks 1 Apr 09, 2018 Graduate Students and Postdocs, STROBE Institutions

Three minute talks about STROBE thesis projects.

STROBE Seminar: Graduate Student 3-Minute Thesis Talks 2 Apr 16, 2018 Graduate Students and Postdocs, STROBE Institutions

Three minute talks about STROBE thesis projects.

STROBE Seminar: IP Seminars at Individual STROBE Institutions Apr 23, 2018 Various Speakers, STROBE Institutions

CU Boulder Seminar Description: If you ever wondered about the different types of Intellectual Property (IP) and strategies in using patents to make an impact, this seminar is for you. We will provide you with an overview of the different types of IP, how it is managed at CU and how the Technology Transfer Office (TTO) can help commercialize your inventions. We will also tell you about a variety of resources to help move your invention forward, regardless of whether you are interested in starting a company. This session will also discuss the importance of protecting confidential information and why a student may wish to obtain a non-disclosure agreement prior to speaking with a third party. 

STROBE Seminar: New Algorithms for Phase Retrieval and Ptychography Apr 30, 2018 Dr. Stan Osher, UCLA

We use splitting methods, suitably modified, to develop new and apparently successful algorithms.

We seem to outperform state of the art when applied to real data obtained by working with Professor Miao's group.