STROBE Press

Scientists see inner workings of enzyme telomerase, which plays key roles in aging, cancer

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Cancer, aging-related diseases and other illnesses are closely tied to an important enzyme called “telomerase.” UCLA researchers report in the journal Cell the deepest scientific understanding yet of this once-mysterious enzyme, whose catalytic core — where most of its activity occurs — can now be seen in near atomic resolution.

Berkeley Lab Paves the Way for Real-time Ptychographic Data Streaming

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CAMERA/ALS/STROBE Collaboration Yields Novel Image Data Workflow Pipeline. Now an inter-government agency funded collaboration of scientists from Berkeley Lab’s DOE-funded Center for Advanced Mathematics for Energy Research Applications (CAMERA), the ALS and STROBE, the National Science Foundation’s Science and Technology Center, has yielded another first-of-its-kind advance for ptychographic imaging: a software/algorithmic pipeline that enables real-time streaming of ptychographic image data during a beamline experiment, providing throughput, compression and resolution as well as rapid...

Hands-on Learning: CU, FLC Scientists Bring Engineering to IMS

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Yes, touch it, ask questions, and learn how it works. That's part of the hands-on science experience that University of Colorado Boulder and Fort Lewis College faculty are taking on the road, encouraging students to consider careers in engineering and technical fields.

Photos: Emerging scientists learn about light and energy

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Dolores School District students... try to figure out what is in the scanning electron microscope after shining a laser beam into it on Tuesday during the Light, Energy and Imaging STEM Workshop inSitter Hall at Fort Lewis College. About 60 students in sixth through 10th grades learned about scale and real-time imaging in the Nano-World, explored photosynthesis and solar energy at the nano-scale and learned about tools that change our perspective on the universe.

One New Honor for 213 Exceptional Individuals: American Academy of Arts and Sciences Elects New Members

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Dr. Henry Kapteyn is elected as a member of the American Academy of Arts and Sciences. CAMBRIDGE, MA | April 18, 2018 — As part of the American Academy of Arts and Sciences’ commitment to recognizing and celebrating excellence, 213 individuals in a wide range of disciplines and professions have been elected as members of the Class of 2018. Founded in 1780, the Academy honors exceptional scholars, leaders, artists, and innovators and engages them in sharing knowledge and addressing challenges facing the world. 

Department of Energy Announces $99 Million for Small Business Research and Development Grants

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STROBE's Markus Raschke received a Phase II STTR to continue work with STROBE industry partner, Anaysis.  82 Grants Will Support Scientific Innovation WASHINGTON, D.C. – U.S. Secretary of Energy Rick Perry announced that the Department of Energy will award 82 grants totaling $99 million to 69 small businesses in 26 states.  Funded through DOE’s Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs, today’s selections are for Phase II research and development.  

UCLA study produces clearest images to date of HSV-1, the virus that causes cold sores

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UCLA researchers have produced the clearest 3-D images to date of the virus that causes cold sores, herpes simplex virus type 1, or HSV-1. The images enabled them to map the virus’ structure and offered new insights into how HSV-1 works. A report on the research was published online by the journal Science. The scientists used cryo electron microscopy, or cryoEM, to obtain the first atomic model of the virus particle, which is made up of more than 3,000 protein molecules comprising tens of millions of atoms.  

Taoiseach Leo Varadkar Awards SFI St. Patrick’s Day Science Medal to Leading Physicist Prof Margaret Murnane and Technology Innovator David McCourt

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Washington D.C., 14th March 2018 – An Taoiseach Leo Varadkar TD, has today presented Science Foundation Ireland’s (SFI) prestigious ‘St. Patrick’s Day Science Medal’ to Professor Margaret Murnane, Professor of Physics and Electrical and Computer Engineering at University of Colorado; and David McCourt, Founder and CEO of Granahan McCourt Capital, for their significant contribution to academia, research and industry.  Now in its fifth year, the SFI St. Patrick’s Day Science Medal recognises the outstanding contributions of Prof Margaret Murnane and David McCourt in their...

APS TV Features STROBE at JILA

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STROBE is featured in an APS TV video about what makes JILA a unique and great place to work. JILA is a unique research and training partnership between the University of Colorado and the National Institute of Standards & Technology. At JILA, scientists develop new research and measurement technologies that broadly advance science and the NIST measurement mission. To date, JILA scientists have been awarded three Physics Nobel Prizes. JILA also trains young innovators who become leaders in industry, academia, and government labs. And after traveling to the many laboratories housed at...

Tracking Energy Flow in Light-harvesting Systems on Native Nanometer and Picosecond Scales

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So Ginsberg and her colleagues devised a measurement that transforms an optical “super-resolution” microscopy known as STED (stimulated emission depletion) into a tracker of excitons on these short scales in an organic semiconductor. The technique makes it possible, for the first time, to relate the characteristics of exciton migration efficiency to nanoscale structures within light harvesting materials. “We ended up using the spatial profile of light pulses and the way that they interact with the material in order to excite very small and localized regions that have very sharp boundaries,”...

Semiconductor nanosensor measures membrane potential

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Professor Shimon Weiss leads team to develop nanosensors that can be directly inserted into a cell’s lipid membrane and be used to measure membrane potential.    The devices, which are based on inorganic semiconductor nanoparticles, could potentially record action potentials from multiple neurons as well as electrical signals on the nanoscale – for example, across just one synapse. Their paper, "Membrane insertion of—and membrane potential sensing by—semiconductor voltage nanosensors: Feasibility demonstration” was published in the January, 12, 2018 issue of Science...

Semiconductor nanosensor measures membrane potential

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Researchers in the US have developed nanosensors that can be directly inserted into a cell’s lipid membrane and be used to measure membrane potential. The devices, which are based on inorganic semiconductor nanoparticles, could potentially record action potentials from multiple neurons as well as electrical signals on the nanoscale – for example, across just one synapse.

Synopsis: Plasmon Thermometers for Silicon

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Electron oscillations in silicon may be used to map, with nanometer resolution, the temperatures across a silicon device. Chris Regan of the University of California, Los Angeles, and co-workers have now developed a thermometry technique that, using a scanning transmission electron microscope (STEM), could eventually map temperature in a silicon device with a resolution down to 10 nm.

Opportunities in Intense Ultrafast Lasers: Reaching for the Brightest Light

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The U.S. is losing ground in a second laser revolution of highly intense, ultrafast lasers that have broad applications in manufacturing, medicine, and national security, says a new report from the National Academies of Sciences, Engineering, and Medicine.  Currently, 80 percent to 90 percent of the high-intensity laser systems are overseas, and all of the highest power research lasers currently in construction or already built are overseas as well.  The report makes five recommendations that would improve the nation’s position in the field, including for the U.S....

Now recording: CU Boulder students, groups produce podcasts

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"From the start, the project has been about giving a platform to voices usually not heard in science class — Latinx voices," said Hernandez Charpak, who is now the assistant director of research and knowledge transfer at CU's STROBE, a National Science Foundation science and technology center on real-time functional imaging.

Subwavelength EUV Imaging

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Tabletop coherent EUV/SXR beams are now possible using high-harmonic generation (HHG).1,2 In addition, a new generation of powerful coherent-diff ractiveimaging (CDI) techniques is removing the resolution limits imposed by traditional X-ray microscopy, by replacing lossy and imperfect X-ray optics with powerful iterative phase retrieval algorithms.

Symposium X—Frontiers of Materials Research

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In her Symposium X talk on Monday, Margaret Murnane of the University of Colorado Boulder described methods to create coherent sources with extremely short wavelengths, with excellent spectral, temporal, and polarization control. “Thirty years ago,” she said, “we never thought that we could achieve the same kind of control—and perhaps better control—over light in extreme UV and soft x-ray region as we could in the visible region of the spectrum.”

STROBE Imaging: How STROBE is modeling the future of research

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From life-saving advances in medicine to life-changing opportunities in renewable energy, imaging technology offers a window into worlds that can’t otherwise be seen by the human eye. That makes it an essential tool across a broad range of scientific disciplines, from engineering to biosciences. But despite their widespread use, today’s imaging techniques remain limited. Finding a solution to this problem will require collaborating with other institutions and developing new ways to educate up and-coming scientists. Based at CU Boulder, the Science and Technology Center on Real-Time...

Manipulating nature with X-ray lasers is topic of Oct. 18 lecture

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Ever since the invention of the laser more than 50 years ago, scientists have been striving to create an X-ray version. But until recently, very high power levels were needed to make an X-ray laser. Making a practical, tabletop-scale X-ray laser source required taking a new approach, as will be described by physicist Margaret Murnane in this fall’s Hans Bethe Lecture.

CU Boulder sets new record in research awards

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The Science and Technology Center on Real-Time Functional Imaging, known as STROBE, will be headquartered at CU Boulder and integrate several areas of imaging science and technology, including photon and electron-based imaging, advanced algorithms, big data analysis and adaptive imaging.

Farther Than the Eye Can See

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The physical lens had been the standard for use in the detailed study of microscopic organisms since Hooke’s seminal work Micrographia was published in 1665. Dr. Jianwei Miao, a professor of Physics and Astronomy and the California NanoSystems Institute at UCLA, blew that standard out of the water with a method known as Coherent Diffractive Imaging (CDI).

2017 OSA Biophotonics Congress: Optics in the Life Sciences - Plenary Presenter Dr. Laura Waller

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Plenary wrap up with Dr. Laura Waller, University of California Berkeley. Computational Microscopy for High-Throughput Science

UCLA physicists map the atomic structure of an alloy

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Researchers measured the coordinates of more than 23,000 atoms in a technologically important material

Scientists Determine Precise 3-D Location and Identity of All 23,000 Atoms in a Nanoparticle

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Berkeley Lab researchers help to map iron-platinum particle in unprecedented detail

Imaging techniques: Nanoparticle atoms pinpointed

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The locations of atoms in a metallic alloy nanoparticle have been determined using a combination of electron microscopy and image simulation, revealing links between the particle's structure and magnetic properties.

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