A STROBE team from the Miao group at UCLA implementated a powerful new tomographic algorithm, termed GENeralized Fourier Iterative REconstruction (GENFIRE), for high-resolution 3D reconstruction from a limited number of 2D projections. GENFIRE assembles a 3D Fourier grid with oversampling and then iterates between real and reciprocal space to search for a solution that is consistent with the measured data and physical constraints. This new algorithms has enabled many new imaging advances.