Building the Microscopes of Tomorrow

The STROBE Science & Technology Center brings together imaging science experts from seven universities and partners with national labs, industry and academe to push the boundaries of imaging science capabilities and technologies, while building a diverse workforce that is prepared for 21st century careers in science and technology.

RESEARCH HIGHLIGHTS

The Swirling Spins of Hedgehogs

A. Rana, C. Liao et al., Nature Nanotechnology, (2023).

Though microscopes have been in use for centuries, there is still much that we cannot see at the smallest . . .

Assessing student engagement with teamwork in an online, large-enrollment course-based undergraduate research experience in physics

A. Werth, et al., Physical Review Physics Education Research, 18, 020128, (2022).

Over the last decade, course-based undergraduate research experiences (CUREs) have been recognized as a way to improve undergraduate science, . . .

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STROBE IN THE NEWS

Humans of JILA: Brendan McBennett

January 13, 2023|JILA|

Surrounded by some of the world’s most advanced lasers, computers, and microscopes sits Brendan McBennett, . . .

Colorado’s quantum revolution

June 28, 2022|CU Boulder Today|

In the 17th Century, a Dutch merchant named Antony van Leeuwenhoek began experimenting with making . . .

STROBE AWARDS

Congratulations to Yuka Esashi for Being Awarded the 2023 SPIE Karel Urbánek Best Student Paper Award

March 2, 2023|SPIE|

At the 2023 Advanced Lithography and Patterning Conference, Yuka Esashi was awarded the SPIE . . .

Congratulations to Brendan McBennett for Being Named as the 2023 Recipient of the Nick Cobb Memorial Scholarship

December 21, 2022|SPIE|

Brendan McBennett has been announced as the 2023 recipient of the $10,000 Nick Cobb Memorial Scholarship by SPIE, . . .

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STROBE IN THE NEWS

Humans of JILA: Brendan McBennett

January 13, 2023|JILA|

Surrounded by some of the world’s most advanced lasers, computers, and microscopes sits Brendan McBennett, . . .

Colorado’s quantum revolution

June 28, 2022|CU Boulder Today|

In the 17th Century, a Dutch merchant named Antony van Leeuwenhoek began experimenting with making . . .

More News

STROBE AWARDS

Congratulations to Yuka Esashi for Being Awarded the 2023 SPIE Karel Urbánek Best Student Paper Award

March 2, 2023|SPIE|

At the 2023 Advanced Lithography and Patterning Conference, Yuka Esashi was awarded the SPIE . . .

Congratulations to Brendan McBennett for Being Named as the 2023 Recipient of the Nick Cobb Memorial Scholarship

December 21, 2022|SPIE|

Brendan McBennett has been announced as the 2023 recipient of the $10,000 Nick Cobb Memorial Scholarship by SPIE, . . .

More Awards

A closer look at spin textures J. Miao, M. M. Mur $A closer look at spin textures J. Miao, M. M. Murnane, Nature Nanotechnology, (2022). DOI: 10.1038/s41565-022-01262-6 Lorentz electron ptychography, a coherent diffractive imaging method, unveils magnetization singularities in a skyrmion lattice in FeGe and captures subtle internal structures near the skyrmion cores, boundaries, and dislocations.$

Roadmap on wavefront shaping and deep imaging in c $Roadmap on wavefront shaping and deep imaging in complex media S. Gigan, O. Katz, H. de Aguiar, E. Andresen, A. Aubry, J. Bertolotti, E. Bossy, D. Bouchet, J. Brake, S. Brasselet, Y. Bromberg, H. Cao, T. Chaigne, Z. Cheng, W. Choi, T. Čižmár, M. Cui, V. Curtis, H. Defienne, M. Hofer, R. Horisaki, R. Horstmeyer, N. Ji, A. LaViolette, J. Mertz, C. Moser, A. Mosk, N. Pégard, R. Piestun, S. Popoff, D. Phillips, D. Psaltis, B. Rahmani, H. Rigneault, S. Rotter, L. Tian, I. Vellekoop, L. Waller, L. Wang, T. Weber, S. Xiao, C. Xu, A. Yamilov, C. Yang, H. Yılmaz, Journal of Physics: Photonics, 4, 042501, (2022). DOI: 10.1088/2515-7647/ac76f9 The last decade has seen the development of a wide set of tools, such as wavefront shaping, computational or fundamental methods, that allow us to understand and control light propagation in a complex medium, such as biological tissues or multimode fibers. A vibrant and diverse community is now working in this field, which has revolutionized the prospect of diffraction-limited imaging at depth in tissues. This roadmap highlights several key aspects of this fast developing field, and some of the challenges and opportunities ahead.$

Electron Diffraction of 3D Molecular Crystals A. $Electron Diffraction of 3D Molecular Crystals A. Saha, S. S. Nia, J. A. Rodríguez, Chemical Reviews, 122, 13883-13914, (2022). DOI: 10.1021/acs.chemrev.1c00879 Electron crystallography has a storied history which rivals that of its more established X-ray-enabled counterpart. Recent advances in data collection and analysis have sparked a renaissance in the field, opening a new chapter for this venerable technique. Burgeoning interest in electron crystallography has spawned innovative methods described by various interchangeable labels (3D ED, MicroED, cRED, etc.). This Review covers concepts and findings relevant to the practicing crystallographer, with an emphasis on experiments aimed at using electron diffraction to elucidate the atomic structure of three-dimensional molecular crystals.$

Untangling the Mechanisms of Lattice Distortions i

Structural and Elastic Properties of Empty-Pore Me $Structural and Elastic Properties of Empty-Pore Metalattices Extracted via Nondestructive Coherent Extreme UV Scatterometry and Electron Tomography J. L. Knobloch, B. McBennett, C. S. Bevis, S. Yazdi, T. D. Frazer, A. Adak, E. E. Nelson, J. N. Hernández-Charpak, H. Y. Cheng, A. J. Grede, P. Mahale, N. Nova, N. C. Giebink, T. E. Mallouk, J. V. Badding, H. C. Kapteyn, B. Abad, M. M. Murnane, ACS Applied Materials & Interfaces, 14, 41316-41327, (2022). DOI: 10.1021/acsami.2c09360 Semiconductor metalattices consisting of a linked network of three-dimensional nanostructures with periodicities on a length scale <100 nm can enable tailored functional properties due to their complex nanostructuring. For example, by controlling both the porosity and pore size, thermal transport in these phononic metalattices can be tuned, making them promising candidates for efficient thermoelectrics or thermal rectifiers. Thus, the ability to characterize the porosity, and other physical properties, of metalattices is critical but challenging, due to their nanoscale structure and thickness. To date, only metalattices with high porosities, close to the close-packing fraction of hard spheres, have been studied experimentally. Here, we characterize the porosity, thickness, and elastic properties of a low-porosity, empty-pore silicon metalattice film (∼500 nm thickness) with periodic spherical pores (∼tens of nanometers), for the first time. We use laser-driven nanoscale surface acoustic waves probed by extreme ultraviolet scatterometry to nondestructively measure the acoustic dispersion in these thin silicon metalattice layers. By comparing the data to finite element models of the metalattice sample, we can extract Young’s modulus and porosity. Moreover, by controlling the acoustic wave penetration depth, we can also determine the metalattice layer thickness and verify the substrate properties. Additionally, we utilize electron tomography images of the metalattice to verify the geometry and validate the porosity extracted from scatterometry...$

Homogeneous, Micron-Scale High-Energy-Density Matt

Observation of formation and local structures of m

High-resolution, wavefront-sensing, full-field pol

Temporal and spectral multiplexing for EUV multibe

Single-Frame Characterization of Ultrafast Pulses $Single-Frame Characterization of Ultrafast Pulses with Spatiotemporal Orbital Angular Momentum G. Gui, N. J. Brooks, B. Wang, H. C. Kapteyn, M. M. Murnane, C. Liao, ACS Photonics, (2022). DOI: 10.1021/acsphotonics.2c00626 Light that carries spatiotemporal orbital angular momentum (ST-OAM) makes possible new types of optical vortices arising from transverse OAM. ST-OAM pulses exhibit novel properties during propagation, transmission, refraction, diffraction, and nonlinear conversion, attracting growing experimental and theoretical interest and studies. However, one major challenge is the lack of a simple and straightforward method for characterizing ultrafast ST-OAM pulses. Using spatially resolved spectral interferometry, we demonstrate a simple, stationary, single-frame method to quantitatively characterize ultrashort light pulses carrying ST-OAM. Using our method, the presence of an ST-OAM pulse, including its main characteristics such as topological charge numbers and OAM helicity, can be identified easily from the unique and unambiguous features directly seen on the raw data─without any need for a full analysis of the data. After processing and reconstructions, other exquisite features, including pulse dispersion and beam divergence, can also be fully characterized. Our fast characterization method allows high-throughput and quick feedback during the generation and optical alignment processes of ST-OAM pulses. It is straightforward to extend our method to single-shot measurement by using a high-speed camera that matches the pulse repetition rate. This new method can help advance the field of spatially and temporally structured light and its applications in advanced metrologies.$

Impacts on student learning, confidence, and affec

Statistical parametrization of cell cytoskeleton r

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Building the Microscopes of Tomorrow

RESEARCH HIGHLIGHTS

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STROBE IN THE NEWS

STROBE AWARDS

STROBE IN THE NEWS

STROBE AWARDS

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